The Physics Society of Iran Iranian Journal of Physics Research 1682-6957 18 3 2019 11 26 Investigation of electrostatic potential of a helical biomolecule in the Debye-Huckel regime by considering the dielectric inhomogeneity Investigation of electrostatic potential of a helical biomolecule in the Debye-Huckel regime by considering the dielectric inhomogeneity 467 475 1377 10.29252/ijpr.18.3.467 FA A Rezaie Dereshgi F Mohammad-Rafiee Journal Article 2019 11 26 Inside living cells, many essential processes involve deformations of charged helical molecules and the interactions between them. Actin filaments and DNA molecules are important examples of charged helical molecules. In this paper, we consider an impermeable double stranded charged molecule in the solvent. According to the nature, the dielectric constant of the molecule is considerably different from that of the bulk. In order to calculate the electrostatic potential in the problem in the Debye-Huckel regime, we find the proper Debye-Huckel Green function for the problem. Using this Green function, we calculate the electrostatic potential in the system. Furthermore, we study the dependence of the electrostatic potential on  the dielectric inhomogeneity, structural parameters and the salt concentration. This study could shed some light on the role of electrostatic interactions in many essential processes involving charged helical molecules such as actin filaments and DNA molecules Inside living cells, many essential processes involve deformations of charged helical molecules and the interactions between them. Actin filaments and DNA molecules are important examples of charged helical molecules. In this paper, we consider an impermeable double stranded charged molecule in the solvent. According to the nature, the dielectric constant of the molecule is considerably different from that of the bulk. In order to calculate the electrostatic potential in the problem in the Debye-Huckel regime, we find the proper Debye-Huckel Green function for the problem. Using this Green function, we calculate the electrostatic potential in the system. Furthermore, we study the dependence of the electrostatic potential on  the dielectric inhomogeneity, structural parameters and the salt concentration. This study could shed some light on the role of electrostatic interactions in many essential processes involving charged helical molecules such as actin filaments and DNA molecules https://ijpr.iut.ac.ir/article_1377_f52378e14237225a6f6c7d802dc6abbd.pdf