Design & construction of a tapered optical fiber sensor for the detection of streptavidin protein

Mazlum Dizaji, Bahareh; Vahedi, Mohammad; Maleki, Ali; Saghafifar, Hossein

doi:10.47176/ijpr.22.3.51454

Design & construction of a tapered optical fiber sensor for the detection of streptavidin protein

Document Type : Original Article

Authors

Bahareh Mazlum Dizaji ¹

Mohammad Vahedi ¹

Ali Maleki ²

Hossein Saghafifar ³

¹ School of Physics, Iran University of Science and Technology, Tehran, Iran

² Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran

³ Optics & Laser Science and Technology Research Center, Malek Ashtar University of Technology, Isfahan, Iran

https://doi.org/10.47176/ijpr.22.3.51454

Abstract

This paper presents the fabrication process and operation of a bio-sensor based on tapered optical fiber by using optical spectrum shift in the presence of PBS buffer and dissolved streptavidin. The taper-fiber sensors are 18 and 24 μm in diameter and are fabricated by use of an oxy-butane torch. The optical spectrum is obtained using a broadband light source and an optical spectrum analyzer (OSA) in a 40 nm wavelength range. The existence of streptavidin on the tapered fiber surface is confirmed. The experiments on PBS buffer have shown that, the output spectrum demonstrates a red-shift by adding the streptavidin. The maximum sensitivity obtained is 29000 nm/RIU.

Keywords

tapered fiber

biosensor

streptavidin

biological buffer

20.1001.1.16826957.1401.22.3.18.2

Subjects

Optics and Photonics

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