Study of biosensor properties of Ag-Au nanocomposite in the vicinity of DNA

Arsalani, S; Ghodselahi, T; Neishaboory, T; Vesaghi, M.A

Study of biosensor properties of Ag-Au nanocomposite in the vicinity of DNA

Authors

S Arsalani

T Ghodselahi

T Neishaboory

M.A Vesaghi

Abstract

Ag, Au nanoparticles and Ag-Au nanocomposite were prepared by co-deposition of RF-sputtering and RF-PECVD from acetylene gas and Ag, Au targets. Atomic structure and topography were investigated by X-ray diffraction (XRD) and atomic force microscopy (AFM), respectively. UV-Visible spectra samples indicated that the activity of Ag and Au nanoparticles in the vicinity of each other increased as the time passed. This result indicated that Ag-Au nanocomposite films demonstrate a higher activity in comparison to Au or Ag nanoparticles thin films. Furthermore, these nanocomposites showed a higher sensitivity in the vicinity of DNA with low concentrations of fM in comparison to Au nanoparticles thin films

Keywords

Ag-Au nanoparticles

SPR

XRD

AFM

DNA biosensor

. M Rycenga, K K Hou, C M Cobley, A G Schwartz, P H C Camargo, and Y Xia, Phys. Chem. Chem. Phys. 11 (2009) 5903.
2. C W Yen, M L Lin, A Q Wang, S A Chen, J M Chen, and C Y Mo. Phys. Chem. C 113 (2009) 17831.
3. J M Wessels, H Nothofer, W E Ford, F Voneorochem, F Scholtz, T Vossmeyer, A Schroedter, H Weller, and A Yasuda. J. Am. Chem. Soc. 126 (2004) 3349.
4. G Suyal, M Mennig, and H Schmidt, Journal of Materials Science 38 (2003) 1645.
5. K Tamada, F Nakamura, M Ito, X Li, and A Baba, Plasmonics 2 (2007) 185.
6. S Zhu and Y Fu. Biomed Microdevices 11 (2009) 579.
8. X Huang, P K Jain, I H El-Sayed, and M A El-Sayed, Nanomedicine 2 (2007( 681.
9. T Ghodselahi, M A Vesaghi, A Shafiekhani, A Baradaran, A Karimi, and Z Mobini. Surface and Coatings Technology 202 (2008) 2731.