Authors
Abstract
Motility and membrane deformation are crucial to motile cells. Therefore formation of protrusion in the membrane has been the subject of various studies. The stable shape of the membrane and also its movements are controlled by the forces exerted by actin filaments. In order to study the protrusion behavior, we represented a toy model based on actin filaments polar characteristic and elastic characteristic of the membrane. We also studied the effect of changing physical parameters such as filament density, the membrane tension, and the polymerization rate on the shape and the magnitude of the protrusion.
Keywords
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2. M J Footer, J WJ Kerssemakers, J A Theriot, and M Dogterom, Direct measurement of force generation by actin filament polymer- ization using an optical trap. Proceedings of the National Academy of Sciences the United States of America 104, 7 (2007) 2181.
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4. A Mogilner and G Oster, Biophysical Journal 84, 3 (2003) 1591.
5. E A Carlsson, Annual Review of Biophysics 39 (2010) 91.
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10. A Atakhani, F Mohammad-Rafiee and A Gholami, Azam. PloS ONE 14, 3 (2019) 0213810.
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15. A Gholami, J Wilhelm, and E Frey, Physical Review E 74, 4 (2006) 041803.
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20. M Deserno and W M Gelbart, Journal of Physical Chemistry B 106, 21 (2002) 5543.
21. A Mogilner and G Oster, Biophysical Journal 71, 6 (1996) 3030.
22. T D Pollard, Journal of Cell Biology 103, 6 (1986) 2747.
23. A Mogilner and B Rubinstein, Biophysical Journal 89, 2 (2005) 782.
24. P K Mattila and P Lappalainen, Nature Reviews Molecular Cell Biology 9, 6 (2008) 446
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